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Cat's Claw

Botanical Name: Uncaria tomentosa

Common name: Una de gato

Overview

Cat's claw (Uncaria tomentosa) is a woody vine native to the Amazon rainforest and other tropical areas of South and Central America. Cat's claw is named after the hook-like thorns that grow along its vine. The bark and root of this herb have been used among indigenous people of the rainforest for centuries to treat a variety of health problems including arthritis, ulcers, sexually transmitted diseases, fevers, and even cancer. Some women consumed cat's claw as a contraceptive because large doses of this herb were believed to cause temporary infertility.
Common Uses
After these claims drew the attention of scientists in Europe, tests began to demonstrate that substances in cat's claw boost the activity of the immune system, reduce inflammation, scavenge damaging particles known as free radicals, and destroy cancerous cells. Today, professional herbalists in the United States and Europe recommend cat's claw to treat inflammatory disorders such as arthritis, viral diseases such as HIV/AIDS, gastrointestinal illnesses such as Crohn's disease, ulcers, and certain cancers. Despite the purported benefits associated with cat's claw, relatively few scientific studies have investigated the safety and usefulness of this herb.
Research
In one study of 13 patients with human immunodeficiency virus (HIV) who refused to take conventional treatments, a dosage of 20 mg cat's claw per day for up to 5 months significantly increased white blood cell counts (the infection-fighting cells in the body that HIV destroys). Cat's claw was also found to boost white blood cell count in rats receiving chemotherapy. (A common side effect of chemotherapy is low white blood cell count.) In another study of 45 people with osteoarthritis of the knee, those who received cat's claw reported a significant reduction in knee pain compared to those who received placebo. Further studies are needed to confirm these preliminary findings, however. Another area that is being studied currently at Oregon Health Sciences University is the use of cat's claw for Alzheimer's disease; no information is available yet to indicate if the herb is helpful or harmful for this condition.

Plant Description

Cat's claw is a thorny vine that can climb as high as 100 feet. It is primarily found in the Amazon rainforest as well as tropical areas in South and Central America. Much of the cat's claw sold in the United States was grown in Peru.
Cat's claw got its name from the curved, claw-like thorns that grow on its stem. The root and bark of cat's claw are the parts used for medicinal purposes.

What's It Made Of?

Cat's claw contains many types of plant chemicals that help reduce inflammation (such as tannins and sterols) and combat certain viruses (such as quinovic acid glycosides).
Cat's claw preparations are made from the root and bark of the of the cat's claw vine. The effectiveness of the root and bark vary depending upon what time of year that portion of the plant is harvested.

Available Forms

The bark of the cat's claw vine can be crushed and used to make tea. Standardized root and bark extracts are also available in either liquid or dried forms.

How to Take It

Pediatric
There are no known scientific reports on the pediatric use of cat's claw. Therefore, it is not currently recommended for children.
Adult

  • Tea: 1 gram (1,000 mg) root bark to 8 ounces water, boil 10 to 15 minutes, cool, and strain. Drink 1 cup three times daily.
  • Tincture (solution made from herb and alcohol, or herb, alcohol, and water): ¼ to ½ teaspoonful two to three times daily
  • Dry, encapsulated standardized extract: 20 to 60 mg daily

Precautions

The use of herbs is a time-honored approach to strengthening the body and treating disease. Herbs, however, contain active substances that can trigger side effects and that can interact with other herbs, supplements, or medications. For these reasons, herbs should be taken with care, under the supervision of a practitioner knowledgeable in the field of botanical medicine.
Although traditional lore indicates that cat's claw is very safe and nontoxic, the American Herbal Products Association (AHPA) gives cat's claw a class 4 safety rating which indicates a lack of scientific data to test that the herb is actually safe. In addition, the AHPA does indicate that the tannin content of cat's claw may cause some abdominal pain or gastrointestinal problems including diarrhea. The diarrhea or loose stools tend to be mild and go away with continued use of the herb.
Cat's claw should not be used by individuals with skin grafts or tuberculosis or by those receiving organ transplants. It should not be used by pregnant or breastfeeding women or by children who are under three years of age.

Possible Interactions

If you are currently being treated with any of the following medications, you should not use cat's claw without first talking to your healthcare provider.
Immunosuppressive Medications
In theory, because cat's claw may stimulate the immune system, this herb should not be used with medications intended to suppress the immune system, such as cyclosporin or other medications prescribed following an organ transplant. This theory has not been tested scientifically.
NSAIDs
Cat's claw may protect against gastrointestinal damage associated with nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen.

 
 

The statements regarding these products have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. The information on this Web site or in emails is for informational and educational purposes only, and is simply a collection of information in the public domain. Information conveyed herein is based on pharmacological and other records - both ancient and modern. No claims whatsoever can be made as to the specific benefits accruing from the use of any herb or nutrients You should not use this information to diagnose or treat any health problems or illnesses without consulting your pediatrician or family doctor. Please consult a doctor with any questions or concerns you might have regarding your or your child's condition.

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Supporting Research

Aquino R, De Feo V, De Simone F, Pizza C, Cirino G. New compounds and anti-inflammatory activity of Uncaria tomentosa. J Nat Prod. 1991;54: 453-459.
Blumenthal M, Riggins C. Popular Herbs in the U.S. Market: Therapeutic Monographs. Austin, Tex: The American Botanical Council; 1997.
Foster S, Tyler VE. Tyler's Honest Herbal. 4th ed. New York: The Haworth Herbal Press; 1999: 97-99.
Karch SB. The Consumer's Guide to Herbal Medicine. Hauppauge, New York: Advanced Research Press; 1999:55-56.
Keplinger K, Laus G, Wurm M, Dierich MP, Teppner H. Uncaria tomentosa (Willd.) DC—ethnomedicinal use and new pharmacological, toxicological and botanical results. J Ethnopharmacol. 1999;64:23–34.
Lemaire I, Assinewe V, Cano P, Awang DV, Arnason JV. Stimulation of interleukin-1 and -6 production in alveolar macrophages by the neotropical liana, Uncaria tomentosa. J Ethnopharmacol. 1999;64:109–115.
Piscoya J, Rodriguez Z, Bustamante SA, Okuhama NN, Miller MJ, Sandoval M. Efficacy and safety of freeze-dried cat's claw in osteoarthritis of the knee: mechanisms of action of the species Uncaria guianensis. Inflamm Res. 2001;50(9):442-448.
Rizzi R, Re F, Bianchi A, De Feo V, de Simone F, Bianchi L, Stivala LA. Mutagenic and antimutagenic activities of Uncaria tomentosa and its extracts. J Ethnopharmacol. 1993;38(1):63-77.
Rotblatt M, Ziment I. Evidence-Based Herbal Medicine. Philadelphia, PA: Hanley & Belfus, Inc; 2002:114-118.
Sandoval M, Charbonnet RM, Okuhama NN, et al. Cat's claw inhibits TNFalpha production and scavenges free radicals: role in cytoprotection. Free Radic Biol Med. 2000;29(1):71-78.
Sheng Y, et al. Induction of apoptosis and inhibition of proliferation in human tumor cells treated with extracts of Uncaria tomentosa. Anticancer Res. 1998;18:3,363–3,368.
Sheng Y, Pero RW, Wagner H. Treatment of chemotherapy-induced leukopenia in a rat model with aqueous extract from Uncaria tomentosa. Phytomedicine. 2000;7(2):137-143.
Steinberg PN. Cat's claw: medicinal properties of this Amazon vine. Nutrition Science News. 1995.